INTELLIGENCE ENGINEERING'S ALPHABET : World Class Biobrains: Drew Endy, Matt Scullin, Daniel Swiger++- BI BioIntelligence, the most collaborative human challenge Mother Earth has ever staged?
NB any errors below are mine alone chris.macrae@yahoo.co.uk but mathematically we are in a time when order of magnitude ignorance can sink any nation however big. Pretrain to question everything as earth's data is reality's judge
Its time to stop blaming 2/3 of humans who are Asian for their consciously open minds and love of education. Do Atlantic people's old populations still trust and celebrate capability of generating healthy innovative brains? What's clear to anyove visting Washington DC or Brussels is a dismal mismatch exists between the gamechanging future opportunities listed below and how freedom of next generation learning has got muddled by how old male-dominated generations waste money on adevrtising and bossing. Consider the clarity of Stanford's Drew Endy's Strange Competition 1 2:
Up to “60% of the physical inputs to the global economy”7 could be made via biotechnology by mid-century, generating ~$30 trillion annually in mostly-new economic activity. 8 Emerging product categories include consumer biologics (e.g., bioluminescent petunias,9 purple tomatoes,10 and hangover probiotics11 ), military hard power (e.g., brewing energetics12 ), mycological manufacturing (e.g., mushroom ‘leather’ 13 ), and biotechnology for technology (e.g., DNA for archival data storage14 ). Accessing future product categories will depend on unlocking biology as a general purpose technology15 (e.g., growing computers16 ), deploying pervasive and embedded biotechnologies within, on, and around us (e.g. smart blood,17 skin vaccines,18 and surveillance mucus19 ), and life-beyond lineage (e.g., biosecurity at birth,20 species de-extinction21 ).		.

notes on drew endy testimony on bio tech 2025 strange competition

Natural living systems operate and manufacture materials with atomic precision on a planetary scale, powered by ~130 terawatts of energy self-harvested via photosynthesis

Biotechnology enables people to change biology. Domestication and breeding of plants and animals for food, service, and companionship began millennia ago. Gene editing, from recombinant DNA to CRISPR, is used to make medicines and foods, and is itself half-a-century old. Synthetic biology is working to routinize composition of bioengineered systems of ever-greater complexity

 https://colossal.com/  20 https://dspace.mit.edu/handle/1721.1/34914  19 https://2020.igem.org/Team:Stanford  18 https://med.stanford.edu/news/all-news/2024/12/skin-bacteria-vaccine.html  17 https://www.darpa.mil/news/2024/rbc-factory  16 https://www.src.org/program/grc/semisynbio/semisynbio-consortium-roadmap/  15 https://www.scsp.ai/2023/04/scsps-platform-panel-releases-national-action-plan-for-u-s-leadership-in-biotechnology/  14 https://dnastoragealliance.org/  13 https://www.mycoworks.com/  12 https://serdp-estcp.mil/focusareas/3b64545d-6761-4084-a198-ad2103880194  11  https://zbiotics.com/  10 https://www.norfolkhealthyproduce.com/  9 https://light.bio/     8 https://web.archive.org/web/20250116082806/https:/www.whitehouse.gov/wp-content/uploads/2024/11/BUILDIN G-A-VIBRANT-DOMESTIC-BIOMANUFACTURING-ECOSYSTEM.pdf  7 https://www.mckinsey.com/industries/life-sciences/our-insights/the-bio-revolution-innovations-transforming-econo mies-societies-and-our-lives     6 https://www.nationalacademies.org/our-work/safeguarding-the-bioeconomy-finding-strategies-for-understanding-ev aluating-and-protecting-the-bioeconomy-while-sustaining-innovation-and-growth   5 https://doi.org/10.1038/s41586-020-2650-9  

  4 https://www.nature.com/articles/s41467-023-40199-9

 AIH- May 2025.Billion Asian womens end poverty networking 2006-1976 is most exciting case of Entrepreneurial Revolution (survey Xmas 1976 Economist by dad Norman Macrae & Romano Prodi). In 2007, dad sampled 2000 copies of Dr Yunus Social Business Book: and I started 15 trips to Bangladesh to 2018- many with apprentice journalists. This is a log of what we found - deepened after dad's death in 2010 by 2 kind remembrance parties hoist by Japan Embassy in Dhaka with those in middle of digital support of what happened next. We witnessed a lot of conflicts - i can try and answer question chris.macrae@yahoo.co.uk or see AI20s updates at http://povertymuseums.blogspot.com. I live in DC region but see myself as a Diaspoira Scot. Much of dad's libraries we transfreered with Dr Yunus to Glasgow University and enditirs og journals of social business, new economics and innovators of Grameen's virtual free nursing school.
Bangladesh offers best intelligence we have seen for sdgs 5 through 1 up to 2008, Search eg 4 1 oldest edu 4.6 newest edu ; .620th century intelligence - ending poverty of half world without electricity -although Keynes 1936 (last chapter General Theiory: Money, Interest, Employment) asked Economists to take hippocratic oath as the profession that ended extreme poverty, most economists have done the opposite. What's not understandable is how educators failed to catalogue the lessons of the handful who bottom-up empowered villages to collaboratively end poverty. There are mainly 2 inteligences to understand- Borlaug on food science -arguable the forst Biointeligence rising ar1950 on; fazle abed on everything that raised life expectancy in tropical village (zero-electricity) asia from low 40s to 60s (about 7 below norm of living with electricity and telecomes). Between 1972 and late 1990s, Abed's lessons catalogued in this mooc had largely built the nation of Bangladesh and been replicated with help of Unicef's James Grant acroo most tropical asian areas. What's exciting is the valley's mr ad mrs steve jobs invted Fazle Abed to share inteligences 2001 at his 65th birthday party. The Jobs and frineds promised to integrate abed's inteligence into neighborhod university stanfrd which in any event wanted Jobs next great leap the iphone. The Valley told abed to start a university so that women graduates from poor and rich nations could blend inteligence as Abed's bottom of the pyramid vilage began their journey of leapfrog modles now that grid infrastructures were ni longer needed for sdiar and mobile. Abed could also help redesign the millennium goals which were being greenwashed into a shared worldwide system coding frame by 2016. There at Abed's 80th birtday party , the easy bit was checking this mooc was uptodate. The hard bit - what did Abed mean by his wish to headhunt a Taiwanese American to head the university's 3rd decade starting 2020?

Sunday, May 21, 2023

My father, Norman Macrae, died 2010 in his 60th year of being probably the only economist to meet and care about the last 7 years of von neumann's work live and so the first 80 years of human artificial intel -

Now ai and economics are ultimately what humans do with maths - so please disregard anyone who noisily says we nees ethics to control ai but not to sack the appalling economics of subprime or other system failures designed in by a dismal segment of western macroeconomists  (and absolutely ghastly media louts) since 1970

AI & BOTTOM+UP END POVERTY VILLAGE ECONOMICS

 i was very privileged to have a gap in my own emotional intel filled by japan ambassador to bangladesh inviting ne to 2 dinners at the Embassy in Dhaka chaired by fazle abed- 

effectively abed told the story of 8 by six year periods of brac (aid 2.0 began in 1972 because the new nation's top down government priotised 2 things - national borders, developing citizens - the 90% left literally out in the dark without electricity it had no relevant knowledge of



 it was left to brac to be the world's largest livelihood training and educational network -one that over 50 years empowered bangladesh village women from illiteracy to nation building- see footnote 1

what really complex about case study of  brac and fazle abed is every 6 years it innovated a bigger wholly innovative half of itself and by the time I met fazle abed it was peaking at about 100000 village practice mentors- 

although abed is certainly the most modest of great leaders he did not believe it was smart to burden brac leadership in bangladesh with any more doubling;

 he had started to look for worldwide partners who would innovate with web and artificial intel; --in hos last 6 years he and jim kim found the same partners and made sure they reviewed the first year of the sdgs from the perspective of educators- quite impossible in 2015 unless the next head of the un (ie today's Guterres) designs tech envoy office to blend education tech and every last mile practice area- so iyt was that you could say abed steve jobs and my father landed on the same pathway


1984 future of personal com networking 

2001 future of mobile collecting data before AI takes over as the only real time analyst of data s

this decade of 2020s where ai for sdgs is our best last chance

given the 2001 dream of steve jobs and fazle abed to open source female grad researchers of sustainability



its easy for me to  love AI like alphafold where a billion years of phd work has been open sourced by londons deep learning 200000 protein database (fridays whitehouse briefing hassibis-whitehouse-ai%20in%20science-19may2023.docx


BUT for 6 weeks now
I have been struggling with chatgpt and brad but finally bard has told me where it wants teachers to experiment with it in new york/bronx so i thought you might like to see the attached

1 bard says  i am a dataset of human dialogues - i am an llm not a gpt
2 i am associated with ai.google- this is a foundation now far larger than google.org and moving in opposite direction of openai since 2019 a business 70% owned by micrisoft and 3 ny fund managers
3 Both I and chatgpt are about 10 times smaller in parameter size than the chinese gpt WU Dao 2.0 - we are also 3 times smaller than megatron-turing a business owned by nvidia and microsoft run out of nvidia santa clara office
4 if you want to help educators and students use tools like me 
survey teachers on their use of Bard : how they have used Bard in their classrooms, what they have found to be the benefits of using Bard, and what challenges they have faced. The survey should also ask teachers for their suggestions on how Bard can be improved. NY Bronx has a longest trusted survey partner of Bard- The Teachers Guild

more in dialogue attached and at economistsocial.com publishers world record book of jobs creation (worldrecordjobs.com)    chris + 1 240 316 8157





 fotnote 1 it amazes me living since 1997 in washingyon dc region that experst praise themselves on a billion people ending extreme poverty but then actually have no knowledge of how th 90% of this population led by asian vilage women did it; they built their own capacities in the vilage to increase life expectancy, to end unnecessary infant deaths and all the while they also became the main export earner; now they had some luck - on health their chalenges were almost exactly the same as tropical chiense woemn; and while unicef actually led the world in reducing chilad mortality james grant made absiolutely sure that nobody got in womens way of exchnaging life critical knowhow without borders; but then his family had been missionaries in china - ithe era of 1972-1997 was indeeed very different; but any politucuan or professor in america who blocks the study of that period from today's americans is at best absolutely useless to the 2020s urgent chalenges if our kids are to be first sustainability generation not the first extinction generation

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