AP July 2025 - INTELLIGENCE ENGINEERING'S ALPHABET : World Class Biobrains: Drew Endy, Matt Scullin, Daniel Swiger++- BI BioIntelligence, the most collaborative human challenge Mother Earth has ever staged?
NB any errors below are mine alone chris.macrae@yahoo.co.uk but mathematically we are in a time when order of magnitude ignorance can sink any nation however big. Pretrain to question everything as earth's data is reality's judge
Its time to stop blaming 2/3 of humans who are Asian for their consciously open minds and love of education. Do Atlantic people's old populations still trust and celebrate capability of generating healthy innovative brains? What's clear to anyove visting Washington DC or Brussels is a dismal mismatch exists between the gamechanging future opportunities listed below and how freedom of next generation learning has got muddled by how old male-dominated generations waste money on adevrtising and bossing. Consider the clarity of Stanford's Drew Endy's Strange Competition 1 2:
Up to “60% of the physical inputs to the global economy”7 could be made via biotechnology by mid-century, generating ~$30 trillion annually in mostly-new economic activity. 8 Emerging product categories include consumer biologics (e.g., bioluminescent petunias,9 purple tomatoes,10 and hangover probiotics11 ), military hard power (e.g., brewing energetics12 ), mycological manufacturing (e.g., mushroom ‘leather’ 13 ), and biotechnology for technology (e.g., DNA for archival data storage14 ). Accessing future product categories will depend on unlocking biology as a general purpose technology15 (e.g., growing computers16 ), deploying pervasive and embedded biotechnologies within, on, and around us (e.g. smart blood,17 skin vaccines,18 and surveillance mucus19 ), and life-beyond lineage (e.g., biosecurity at birth,20 species de-extinction21 ).
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notes on drew endy testimony on bio tech 2025 strange competition

Natural living systems operate and manufacture materials with atomic precision on a planetary scale, powered by ~130 terawatts of energy self-harvested via photosynthesis

Biotechnology enables people to change biology. Domestication and breeding of plants and animals for food, service, and companionship began millennia ago. Gene editing, from recombinant DNA to CRISPR, is used to make medicines and foods, and is itself half-a-century old. Synthetic biology is working to routinize composition of bioengineered systems of ever-greater complexity

 https://colossal.com/  20 https://dspace.mit.edu/handle/1721.1/34914  19 https://2020.igem.org/Team:Stanford  18 https://med.stanford.edu/news/all-news/2024/12/skin-bacteria-vaccine.html  17 https://www.darpa.mil/news/2024/rbc-factory  16 https://www.src.org/program/grc/semisynbio/semisynbio-consortium-roadmap/  15 https://www.scsp.ai/2023/04/scsps-platform-panel-releases-national-action-plan-for-u-s-leadership-in-biotechnology/  14 https://dnastoragealliance.org/  13 https://www.mycoworks.com/  12 https://serdp-estcp.mil/focusareas/3b64545d-6761-4084-a198-ad2103880194  11  https://zbiotics.com/  10 https://www.norfolkhealthyproduce.com/  9 https://light.bio/     8 https://web.archive.org/web/20250116082806/https:/www.whitehouse.gov/wp-content/uploads/2024/11/BUILDIN G-A-VIBRANT-DOMESTIC-BIOMANUFACTURING-ECOSYSTEM.pdf  7 https://www.mckinsey.com/industries/life-sciences/our-insights/the-bio-revolution-innovations-transforming-econo mies-societies-and-our-lives     6 https://www.nationalacademies.org/our-work/safeguarding-the-bioeconomy-finding-strategies-for-understanding-ev aluating-and-protecting-the-bioeconomy-while-sustaining-innovation-and-growth   5 https://doi.org/10.1038/s41586-020-2650-9  

  4 https://www.nature.com/articles/s41467-023-40199-9

AIH- May 2025.Billion Asian womens end poverty networking 2006-1976 is most exciting case of Entrepreneurial Revolution (survey Xmas 1976 Economist by dad Norman Macrae & Romano Prodi). In 2007, dad sampled 2000 copies of Dr Yunus Social Business Book: and I started 15 trips to Bangladesh to 2018- many with apprentice journalists. This is a log of what we found - deepened after dad's death in 2010 by 2 kind remembrance parties hoist by Japan Embassy in Dhaka with those in middle of digital support of what happened next. We witnessed a lot of conflicts - i can try and answer question chris.macrae@yahoo.co.uk or see AI20s updates at http://povertymuseums.blogspot.com. I live in DC region but see myself as a Diaspoira Scot. Much of dad's libraries we transfreered with Dr Yunus to Glasgow University and enditirs og journals of social business, new economics and innovators of Grameen's virtual free nursing school.
Bangladesh offers best intelligence we have seen for sdgs 5 through 1 up to 2008, Search eg 4 1 oldest edu 4.6 newest edu ; .620th century intelligence - ending poverty of half world without electricity -although Keynes 1936 (last chapter General Theiory: Money, Interest, Employment) asked Economists to take hippocratic oath as the profession that ended extreme poverty, most economists have done the opposite. What's not understandable is how educators failed to catalogue the lessons of the handful who bottom-up empowered villages to collaboratively end poverty. There are mainly 2 inteligences to understand- Borlaug on food science -arguable the forst Biointeligence rising ar1950 on; fazle abed on everything that raised life expectancy in tropical village (zero-electricity) asia from low 40s to 60s (about 7 below norm of living with electricity and telecomes). Between 1972 and late 1990s, Abed's lessons catalogued in this mooc had largely built the nation of Bangladesh and been replicated with help of Unicef's James Grant acroo most tropical asian areas. What's exciting is the valley's mr ad mrs steve jobs invted Fazle Abed to share inteligences 2001 at his 65th birthday party. The Jobs and frineds promised to integrate abed's inteligence into neighborhod university stanfrd which in any event wanted Jobs next great leap the iphone. The Valley told abed to start a university so that women graduates from poor and rich nations could blend inteligence as Abed's bottom of the pyramid vilage began their journey of leapfrog modles now that grid infrastructures were ni longer needed for sdiar and mobile. Abed could also help redesign the millennium goals which were being greenwashed into a shared worldwide system coding frame by 2016. There at Abed's 80th birtday party , the easy bit was checking this mooc was uptodate. The hard bit - what did Abed mean by his wish to headhunt a Taiwanese American to head the university's 3rd decade starting 2020?

Tuesday, August 12, 2025

Bangladesh Embassy DC - 20 year review of yunus blue book future capitalism before elections early 2026

 Draft 1 commentary - do you have any edits?

Yunus is expected to hand over interim leadership with elections early 2026

Blue Book - Social Business - Future of Capitalism was (ghost) written first 6 months of 2007 after Yunus won Nobel Peace Prize (lobbied for by Clintons). It offers a missing jigsaw piece to all asian human development economics but not if solely coordinated by Yunus. Deeper entrepreneurs were Fazle Abed and are the Quadir family. (As a Diaspora scot,  after 13 trips to bangladesh I decided I am totally unable to study which political or faith leaders did what as human's 8th largest population and deepest end poverty miracle scaled 1971-2019, but yunus, abed, quadirs merit being in any intelligence hall of fame EconomistDiary.com : AI Games: Architect Intelligence ). After Sir Fazle Abed's death, i have focused my limited budget and personal travel updates on Hong Kong and Taiwan. 

 Review copies which my family made available to Economist journalists and Japan Embassies  were available from fall 2007, and I first met Yunus at Grameen Bank xmas 2007. We then sampled 2000 Blue books from early 2008 across Europe and East coast US. Intelligence roots came from Yunus book tour USA January 2008, UK February, French edition April (important because the idea of global social business partnerships was Parisian (Danone and HEC Business School chapter 6 pp 129), later Berlin...

The book can help open maps to Asia most conflicting Geonomics (post colonial ai) puzzles as well as offering behavioral insights into living through 4 tech revolutions in one intergeneration from 1995-2025 (community networking through chips*satellite clouds*AI accelerated supercomputers) but partly  because it was ghosted it leaves out most of yunus investment sources and other core entrepreneurs like Brac Fazle Abed and the tech village phone revolution which the Quadir brothers started with Yunus. As early as January 2008, Yunus saw subprime coming. He was expecting Obama and Clintons (who first met him 1989!) would ask for his help in Jan 2009. 

When my father The Economist's Norman Macrae hosted Yunus social business lunch in London Royal Automobile Club feb 2008. Subprime was puzzle number 2 interesting my father. Because dad had been stationed in Bangladesh region (spending last days as teenage navigator ww2 allied bomber command burma campaign and my mother's family work on India's Independence) Puzzle number 1 pp 124-8 how had Asia coastal development stopped at Myanmar/Bangladesh. You can follow from late 1950s development of superports in Japan, Korea S, Taiwan, HK, Singapore . Their supply chains manufactured microelectronics doubling chip power every 18 months from 1965 as well as Geonomic maps shared by JF Kennedy and the 2 Royal families of UK, Japan 1962-3 EconomistJapan.com . From late 1980s superport knowhow was also linked in by Chinese Diaspora from north to south on china coast from beijing to south down china coastline but stopped at Myanamar/Bangladesh. Bengali Bayspeople had been partitioned ff from what had been the 19th century's number 1 superport Calcutta; most of bengal bay and myanmar have for 80 years been the infrastructure block to all asians enjoying superport world trade and the ever larger win-win cake of real and artificial intelligence.

In  worldwide mapping contexts,  the book puzzles show how broken all USAID was as well as human development economics of clintons (who first visited Yunus in Bangladesh 1989 at about the same time as he was helping Obama;s mom in Indonesia as testified to by jim kiim Hacking the World Bank - Freakonomics) , Biden, Obama, and how broken youth-investment broken EU was in responding to 1 fall of berlin wall, 2 after 9/11, after subprime.


Bangladesh is also the history of digital transfromation and energy  puzzles: the quadit brothers brough village phones from pp 78   and solar pp79 to Bangladesh even before this was brought to village china (all very sudden 1995)
Abed had started scaling women empowerment across 100000 people communities (15000 village women householders per brac branch) at a time in 1972. That's 11 years before Grameen Bank Ordinance 1983. Abed had scaled food and health social businesses. With James Grant his networks were sharing oral rehydration and vaccination knowhow with china's tropical villages. Abed was launching 40000 primary schools village education   This was not the ashoka model of changing one life at a time - as abed said in bangladesh: small may be beautiful but large scale is absolutely essential. When village phones came to Bangladesh- the quadirs got yunus a licence at pennies in dollar and grameen phone was launched as a hybrid- big telecom company, grameen village telephone ladies. A japanese company in silicon valley helped abed install a corporate intranet. One of yunus problems is his pure social business ,model takes too much out as women members dividends that tech companies from 1995 needed reinvesting in.

2008-10 As subprime caused west to disinvest in youth, my family sampled 2000 yunus books across europe and east coast usa. After dads death in 2010, the Japan Embassy in 2012 hosted 2 roundtables with Fazle Abed and the quadiur family to understand review everything including yunus forfeiture of grameen bank to hasina and transfer of quadirs from supporting yunus to fazle abed - building bkash with Gates and jack ma's alipay. Glasgow Adam Smith University took over my father's main library and started publishing Social Business Journal so we know Yunus story from every European country's fan groups including his continuing role in shaping Olympics. 

At Abed's 80th birthday party dhaka 2016, Gates and Ma assembled with fei-fei li the un transformation of education and ai for good model but this map of UN2.0 got lost end of 2019 with death of abed , start of covid,,, as well as Trump's end of American aid


is a great supporter of Muhammad Yunus and women empowerment. As India Agentic AI experiment becomes AI most populous transformation both of India and S Asia , will bangladesh be included. It seems Youth's forgiveness of Hasina in Delhi is the urgent potential stumbling block.

Abed's deepest partnerships today include first lady of qatar and Singapore Universities, potentially melinda gates but she has failed to connect this with eomens ai in asia. While Yunus was well understood by Japan's PM Abe, he has somewhat unnerved Prince Charles and Japan Emperor families partly because he did not share all his solar energy knowledge openly in 2000s.  

You can dig through Bangladesh moments in history some other interesting dates potentially relevant to ABCDE of human development economics and world bank/multilateral future possibilities

1995 womens summit beijing - essentially this was last summit before village telecoms and solar and united brac and chinese knowhow round barefoot medics, food and schools networks.

One good thing happened in 2001 before 9/11. Steve Jobs hosted 65th birthday party of Fazle Abed in Silicon Valley. From then on west coast-pacific and east coast atlantic has been 2 different stories of world futures - little sister vs big brother. Steve Jobs agreed Abeds dream of changing roles of graduate women engineering. He worked with nvidia yahoo and Tsai-Softbank and stanford on that before designing a university in a phone and having his life curtailed by cancer.

So the blue book merits being in any entrepreneurial revolution library but needs contextual parsing

Sincerely

Chris Macrae Bethesda MD + 1 240 316 8157

Friday, August 1, 2025

25-35 most exciting time to be alive- are teachers as well as students actioning this?

Our web's name CatholicUni.com celebrates the remarkable fact that the greatest learning miracle 1970-1995 occurred amongst asia village rural women networks who adapted Brazilian Paulo Freire servant leadership and community gravitated culture. Latin Americans may also tell you that around the time of moon landing ie lat 1960s, a continental dialogue was held. Colonisation of Latin America made catholicism the number 1 faith /culture but which type of catholicism matches latino needs. It was decided that Franciscan servant leader values mattered. Interestingly the valley between San Francisco and Santa Clara reflects the same view. St Francis asked for women followers the Clares to help spread maternal an infant health networking where missions spread; while male followers of francis were concerned with nature's diversity. Whilst it has to be admitted that most of the goals multilaterals demaned millennials focused on have not yeat materialised, early advanceds of 2000s Global Fund relied deeply on the energies of eg Paul Farmer, Jim Kim , Fazle Abed. All of whom practised servant leadersip with the poorest they aimed to heal. Paul Farmer explained the importamce of hope culture if a nations smartest young medics are to give time to eg doctoirs without borders or indeed to training barefoot nurses

 Thanks to AI , 2025-35 is the most exciting decade to reward curious minds. There isnt a professional skill that cant be brilliantly improved with AI. This means both teachers and students need to chnage hw they spend their time. Action/experiential flow learing in; examining individuals for lack of intelligence is out. It may be obvious with eg music or sports that learning involves practice. Its even more so with being AI competent. Any country that doesnt chnage how its teachers and students sends their time will lose out deeply - whether that country has preiously been one of the world's most advanced or least developed. Morever context matters. 2o years before digital networking begain in the 1990s , rural women emopwerment movements in asia developed contextaul learning networks in extraordinary ways. They needed to do this to improve life expectancy with many girls need=ing to action learn basics of nursing as early as age 11. In places where schooling is only guat=ranteed to 11 (see eg un gials up to 2015) its a tragedy if girls in particual dont learn basic health services to each other and infants at school. Actually the lancet has extended this to proposing that peer to peer health is the biggest missing curriculum of all graded 3 to 8 ie preteen age 9 up to 15; - smart places will p;lug in to chats basic first aid knowhow to celebrate peer to peer physical and mental health as one of colest ways to spend time chatting with friiends.


 AI is making 25-35 the most exciting decade ever fir action learning. Its shocking in richer nations how few teachers are helping students prepare for that. The great development miracles of the last half century eg brac networks bangladesh designed by a shell oil engineer ceo turned servant leader celebrate experiential learning. See also  Prof csik's work which shows that genii maximise time spent at experiential edge of the genii context

Those present at Abed's 80th birthday party in 2016 will know he asked that september unga 2016 would map how to include ai in transformative education modeling - jim kim, melinda gates fei-fei li chaired report for gutteress in which a transformative education model had 5 components - 4 surrounding a coire of  3)AI for good


2 of elements were change how 1 teachers spend their time , 2 students spend their time

4 was coect youth learning spaces with advanceess in  5G, 6G, etc

5 code deep data


Monday, July 21, 2025

This month Nvidia's Jensen Huang said this about urgency required to transform education
July 2025, Jensen Huang: 1730 It is vital that everyone engages AI right away. Every adult, every working person, not working person, every child should address and engage AI right away. And the reason for that is because AI is the greatest equalization equalizing force. It is the first time in history that a technology as incredible as artificial intelligence is useful for someone who knows how to program software, no historical experience of how to use a computer. This is the very first time in history that all of a sudden that computer is easy to use. If you don't know how to use AI, just open up the website, go to Chat GPT, go to Gemini Pro or Grom 3/4 - just ask a simple question. . And you could even say, "I have no idea how to use AI. Can you teach me how to use AI?" And if you don't know how to type, hit the microphone button and speak to us.. And if you don't understand English, you can speak whatever language you like. It is an extraordinary thing. And I also think it's incredible that if the AI doesn't know that language, you tell the AI go learn that language, right? And so so I think everybody needs to to engage AI. It is the greatest equalization um uh equalization force that we have ever known and it's going to empower.. it's going to enable... it's going to lift society of all you know everywhere.

Let's suppose teacher training courses don't yet expect teachers to value jensen's view - we asked grok for some short lesson plans for teacher training courses. (This is i=our 43rd year of arguing that the tech of computers satellites and chips require millennials brains to be valued in a different way that the over-examined classroom. we'd happily work with you on more detailed questions to grok on lesson plans as this is just a sampler

Grok3 recommendation:

Jensen Huang’s vision of AI as an accessible, equalizing force is not yet fully reflected in K–12 or college teacher training. Below are short lesson plans to inspire teachers across grade levels to embrace this priority:
  • K–5: “AI as a Storytelling Buddy” (1 hr): Teachers use Grok 3’s voice input to create stories in local languages, designing inclusive activities. Outcome: Belief in AI’s accessibility for young learners [web:10].
  • Grades 6–8: “AI as a Problem-Solving Partner” (1.5 hrs): Teachers explore AI for math/science problems, creating inquiry-based lessons. Outcome: Confidence in AI’s no-code potential [web:10].
  • Grades 9–12: “AI as a Research Assistant” (1.5 hrs): Teachers use AI for research (e.g., health disparities), designing ethical projects. Outcome: Belief in AI’s equity for diverse students [web:0].
  • College (12–15): “AI as a Collaborative Innovator” (2 hrs): Instructors design interdisciplinary AI projects (e.g., health equity), ensuring data sovereignty. Outcome: Embrace of AI’s global innovation potential [web:7].

Friday, May 16, 2025


Thanks to DE for most exciting network to follow in these BIo20s wwe.catholicuni.com and ai20s.com drewendy.bsky.social chat BI1 of 100 do you know about turning dandelions into latex?

WHATS CONNECTION BETWEEN WI AI BI? womens intel, engineering intel aka AI, Biogeneration Intel?  from 2024 stanford first report of interactions of 10 emerging technolgy this website chnaged priority of its case study search yet again - we now invite help on 100 most unbelievable but true biotechnolgy stories rsvp chris.macrae@yahoo.co,uk Wash DC Region & Glasgow U, ED of ST James London, Bangladesh hi-trust Diarist since 2007,   & linkedin unwomens substack chrismacrae, co-author of 1984's future hoistiry 2025report, archivist Neumann-einstein-turing diaries collected by The Economist from 1951/

previously we have stidied since 1951 expectaions Neumann-Einstein-Turing had of their legancy and by how 1962 Kennedy, Japan & British Royal families were first to undersatnd intergenerational chalengges of NET's 10**18 more human tech by 2025- could this integrate with anture's system maps as adam smith first asked in 1758 with nature's tech - maths of which was tranformed by einstein's 1905 publication of e=mcsquared  ...more