INTELLIGENCE ENGINEERING'S ALPHABET : World Class Biobrains: Drew Endy, Matt Scullin, Daniel Swiger++- BI BioIntelligence, the most collaborative human challenge Mother Earth has ever staged?
NB any errors below are mine alone chris.macrae@yahoo.co.uk but mathematically we are in a time when order of magnitude ignorance can sink any nation however big. Pretrain to question everything as earth's data is reality's judge
Its time to stop blaming 2/3 of humans who are Asian for their consciously open minds and love of education. Do Atlantic people's old populations still trust and celebrate capability of generating healthy innovative brains? What's clear to anyove visting Washington DC or Brussels is a dismal mismatch exists between the gamechanging future opportunities listed below and how freedom of next generation learning has got muddled by how old male-dominated generations waste money on adevrtising and bossing. Consider the clarity of Stanford's Drew Endy's Strange Competition 1 2:
Up to “60% of the physical inputs to the global economy”7 could be made via biotechnology by mid-century, generating ~$30 trillion annually in mostly-new economic activity. 8 Emerging product categories include consumer biologics (e.g., bioluminescent petunias,9 purple tomatoes,10 and hangover probiotics11 ), military hard power (e.g., brewing energetics12 ), mycological manufacturing (e.g., mushroom ‘leather’ 13 ), and biotechnology for technology (e.g., DNA for archival data storage14 ). Accessing future product categories will depend on unlocking biology as a general purpose technology15 (e.g., growing computers16 ), deploying pervasive and embedded biotechnologies within, on, and around us (e.g. smart blood,17 skin vaccines,18 and surveillance mucus19 ), and life-beyond lineage (e.g., biosecurity at birth,20 species de-extinction21 ).
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notes on drew endy testimony on bio tech 2025 strange competition

Natural living systems operate and manufacture materials with atomic precision on a planetary scale, powered by ~130 terawatts of energy self-harvested via photosynthesis

Biotechnology enables people to change biology. Domestication and breeding of plants and animals for food, service, and companionship began millennia ago. Gene editing, from recombinant DNA to CRISPR, is used to make medicines and foods, and is itself half-a-century old. Synthetic biology is working to routinize composition of bioengineered systems of ever-greater complexity

 https://colossal.com/  20 https://dspace.mit.edu/handle/1721.1/34914  19 https://2020.igem.org/Team:Stanford  18 https://med.stanford.edu/news/all-news/2024/12/skin-bacteria-vaccine.html  17 https://www.darpa.mil/news/2024/rbc-factory  16 https://www.src.org/program/grc/semisynbio/semisynbio-consortium-roadmap/  15 https://www.scsp.ai/2023/04/scsps-platform-panel-releases-national-action-plan-for-u-s-leadership-in-biotechnology/  14 https://dnastoragealliance.org/  13 https://www.mycoworks.com/  12 https://serdp-estcp.mil/focusareas/3b64545d-6761-4084-a198-ad2103880194  11  https://zbiotics.com/  10 https://www.norfolkhealthyproduce.com/  9 https://light.bio/     8 https://web.archive.org/web/20250116082806/https:/www.whitehouse.gov/wp-content/uploads/2024/11/BUILDIN G-A-VIBRANT-DOMESTIC-BIOMANUFACTURING-ECOSYSTEM.pdf  7 https://www.mckinsey.com/industries/life-sciences/our-insights/the-bio-revolution-innovations-transforming-econo mies-societies-and-our-lives     6 https://www.nationalacademies.org/our-work/safeguarding-the-bioeconomy-finding-strategies-for-understanding-ev aluating-and-protecting-the-bioeconomy-while-sustaining-innovation-and-growth   5 https://doi.org/10.1038/s41586-020-2650-9  

  4 https://www.nature.com/articles/s41467-023-40199-9

AIH- May 2025.Billion Asian womens end poverty networking 2006-1976 is most exciting case of Entrepreneurial Revolution (survey Xmas 1976 Economist by dad Norman Macrae & Romano Prodi). In 2007, dad sampled 2000 copies of Dr Yunus Social Business Book: and I started 15 trips to Bangladesh to 2018- many with apprentice journalists. This is a log of what we found - deepened after dad's death in 2010 by 2 kind remembrance parties hoist by Japan Embassy in Dhaka with those in middle of digital support of what happened next. We witnessed a lot of conflicts - i can try and answer question chris.macrae@yahoo.co.uk or see AI20s updates at http://povertymuseums.blogspot.com. I live in DC region but see myself as a Diaspoira Scot. Much of dad's libraries we transfreered with Dr Yunus to Glasgow University and enditirs og journals of social business, new economics and innovators of Grameen's virtual free nursing school.
Bangladesh offers best intelligence we have seen for sdgs 5 through 1 up to 2008, Search eg 4 1 oldest edu 4.6 newest edu ; .620th century intelligence - ending poverty of half world without electricity -although Keynes 1936 (last chapter General Theiory: Money, Interest, Employment) asked Economists to take hippocratic oath as the profession that ended extreme poverty, most economists have done the opposite. What's not understandable is how educators failed to catalogue the lessons of the handful who bottom-up empowered villages to collaboratively end poverty. There are mainly 2 inteligences to understand- Borlaug on food science -arguable the forst Biointeligence rising ar1950 on; fazle abed on everything that raised life expectancy in tropical village (zero-electricity) asia from low 40s to 60s (about 7 below norm of living with electricity and telecomes). Between 1972 and late 1990s, Abed's lessons catalogued in this mooc had largely built the nation of Bangladesh and been replicated with help of Unicef's James Grant acroo most tropical asian areas. What's exciting is the valley's mr ad mrs steve jobs invted Fazle Abed to share inteligences 2001 at his 65th birthday party. The Jobs and frineds promised to integrate abed's inteligence into neighborhod university stanfrd which in any event wanted Jobs next great leap the iphone. The Valley told abed to start a university so that women graduates from poor and rich nations could blend inteligence as Abed's bottom of the pyramid vilage began their journey of leapfrog modles now that grid infrastructures were ni longer needed for sdiar and mobile. Abed could also help redesign the millennium goals which were being greenwashed into a shared worldwide system coding frame by 2016. There at Abed's 80th birtday party , the easy bit was checking this mooc was uptodate. The hard bit - what did Abed mean by his wish to headhunt a Taiwanese American to head the university's 3rd decade starting 2020?

Sunday, September 24, 2023

AIGames.solar we invite everyone to play AI Games by naming who they see as most unique;y having advanced the human lot 1950-2025. Here is 2023-2-24  top 20. There is so much to be done if the younger half of the world is to be the first sustainability generation that our selections are passed towards the living - only tow have passed. (1 Steve Jobs and Fazle Abed). If we were to make this representative of all 75 years ; the first maths great we'd include Von Neumann; the agricultural great Borlaug; the quality systems great deming; JF Kennedy the most pro-youth world leader. UNICEFs health great James Grant would defimtely need theit intelligenvce integrated.

 Of course there is no perfect selection- whats the ,ost urgent crisis facing the community yo care most about? We welcome other nominations - but here's a quck tour around these 20 as well as what to see now esdpecialy if you are teacher or student 23-24 wanting milennaisl to be first sdgeneration

More than anyone else it was the inteligence of Borlaug and Abed that raised life expecatncies in pooresdt nations of the 20th century from low 40s to at least 60. That builds an extra generation into family building - making eg higehrer education more viable. Until that happens almost every undedeveloped country priotises boys lives over girls Even as the 20th c came tio a close its not that clear that thre ehalves of the world , women youth, porest get more than 10% voice in the future and to be in ll three of those populations - the main group an=bed lived to empower needed the most unique intellignece. Styeve Jobs also had an unique intelignece. So it was great that he chsoe to host silicon valey's 65th birthday wish party for fazle abed in 2001. The two of them agreed they would do everything they could to transform 21st c university at least as far as afemale empowerin =ng alumni wished to colaborate around the inteligencve abed was now 30 years into building and little more than 5 year of partnersbrining him solar and mobile to vilages previousy without any grids (no electricity- no telecomsd- no piped wayer) 


we have put fei-fei lei and hasabis in teh centre since it has bene their combined work since fei-fel li aladed at stanford asnd was greeted by ng and yang, that has revolutionised AI. In fact mathematically its reconnecetd with von neumann's depeest questions on neuroscience- what will the mutually good impacts of human brain and computer brain be. Both london based hassabis and fei-fei li had doen neurosceience doctiraes and concluded if we spend however long it takes to code computiang machines so vision what humans see including everuthing humans have written, then totally diferent comoutaional pssibilities will merge than when programing langaues are as abstract as the binary 0/1s they are fiunded on. 


The oarterships both interpersonal and organisational betwwe groupd 5,9,8, 6 are very interedting - thise based in silicon valley may have more info- what we can do is foolw r=through what both fei-fe and demis did from 2009 as well as add details when theyu connect with paricuar people

hassabis was an early winner of fei-fei li imagent competition funder by nsf hosted out of stanford; he was pretraining compouters on the game of go; he needed huge computing resources so was happy to make a merger with google in 2014; at which stage it is believed he made a billion dollar donation to fei-fei li's rearch; probanly brin and page had already taken notice- anyhow as alumn of stafird they started investing there and at 2017 conclusion annuage imagenet unvited fei-fei yo co-direct google cloud unit; by 2017 she had already been noticed by melinda gates who was starting her own philanthropy - gates and ceo of v=nvidia became first funders if the schools ai curricula edited by fe-fei li www.ai-4-all.org; 2017 saw guterres take lead of the un and its 17 sdgs; jim kim and others had shated with guterres (they were old friends from guterres red cross days) ; so guterres asked melinda gates to co-chair a year long stsem tranfirmation raodmap - see un tech envoy- by 2017 geneva' itu had pit aiforggod inthe centre of gov 2 roadmapping; melimda gates 3rd move with her foundation is poublishing women empowermnt books "momemt of lift" fei-fei book worlds i see will be the feature of 23-24; by now support with melinda gates and other leading women around silicon valley includes prisciloa chan , condoleezza rice, jennifer doudno; back in 2017 qqatars first lady sheu=il moza was un hub of all refugee education- she had been building theoworld's number 1 womens educational camoud, and histed the global ed laureaes with faxle abed as fer first prize winner- back in 2023 sheika moza co-chiaring un panel with guterres


one of un relative weakness along withb whileb multilaterals is thatybits experts dont explain their practice intel often inside usa thiugh it could be e=usa -it a huge possibility if brooklyns 2 great benefactirs of womens and inner city adavances can someho help un stage win-win events- mrs tsai has founded the main neuroscience schools in stafrd and yale; she owns several sports platform offering a way to develop women sports o=possible inoacts on youth 


mrs tandon is benefaxtir of brr=oolyn nyu engineering college and suporter of women in maths and engineering as well as potential connector with india- amandeep gill un tech envoy is india-un civil servant

This party awakened silicon valley people in at least 2 senses. Gates and all westren health inteleigencs for the poorest saw and parnered fazle abed in what became known as the globla. Within this fund Abed had the mostefefetice solution for fighting rural tuberculosis. TB and hiv also multiplied each other somethung that Jim Kim made sure both the who and us nationa l industries of helth recoginsed - it was kim who linked te dpeest partners of making hiv emdicine affiradbale eveywgere as well as expedeiting its research

With two thirds of humans in asia, and perhaps less than 25% directly anu=imating arcto ocean trade, the deepest data advances are needed out of east and south. At stanfrd this concerned mooc founder ng and koler, as well as yang who was selling out his foudners stake of yahoo to help maximise 360 degree alumni at stanford.



 My main professsional role since 1973 Postgrad Diploma Stats at Cambidge Maths Lab DAMTP has been surveyoong peoples behavior and explaining to powerful decision makers something their daya had not shown them before. This dobetailed with my afther's life work which was a joint diaris of von neumann's life work and thet if Economist founder James Wilson.

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