DCAI--AI & Childhood Cancer ...AP July 2025 - INTELLIGENCE ENGINEERING'S ALPHABET : World Class Biobrains: Drew Endy, Matt Scullin, Daniel Swiger++- BI BioIntelligence, the most collaborative human challenge Mother Earth has ever staged?
NB any errors below are mine alone chris.macrae@yahoo.co.uk but mathematically we are in a time when order of magnitude ignorance can sink any nation however big. Pretrain to question everything as earth's data is reality's judge
Its time to stop blaming 2/3 of humans who are Asian for their consciously open minds and love of education. Do Atlantic people's old populations still trust and celebrate capability of generating healthy innovative brains? What's clear to anyove visting Washington DC or Brussels is a dismal mismatch exists between the gamechanging future opportunities listed below and how freedom of next generation learning has got muddled by how old male-dominated generations waste money on adevrtising and bossing. Consider the clarity of Stanford's Drew Endy's Strange Competition 1 2:
Up to “60% of the physical inputs to the global economy”7 could be made via biotechnology by mid-century, generating ~$30 trillion annually in mostly-new economic activity. 8 Emerging product categories include consumer biologics (e.g., bioluminescent petunias,9 purple tomatoes,10 and hangover probiotics11 ), military hard power (e.g., brewing energetics12 ), mycological manufacturing (e.g., mushroom ‘leather’ 13 ), and biotechnology for technology (e.g., DNA for archival data storage14 ). Accessing future product categories will depend on unlocking biology as a general purpose technology15 (e.g., growing computers16 ), deploying pervasive and embedded biotechnologies within, on, and around us (e.g. smart blood,17 skin vaccines,18 and surveillance mucus19 ), and life-beyond lineage (e.g., biosecurity at birth,20 species de-extinction21 ).
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notes on drew endy testimony on bio tech 2025 strange competition

Natural living systems operate and manufacture materials with atomic precision on a planetary scale, powered by ~130 terawatts of energy self-harvested via photosynthesis

Biotechnology enables people to change biology. Domestication and breeding of plants and animals for food, service, and companionship began millennia ago. Gene editing, from recombinant DNA to CRISPR, is used to make medicines and foods, and is itself half-a-century old. Synthetic biology is working to routinize composition of bioengineered systems of ever-greater complexity

 https://colossal.com/  20 https://dspace.mit.edu/handle/1721.1/34914  19 https://2020.igem.org/Team:Stanford  18 https://med.stanford.edu/news/all-news/2024/12/skin-bacteria-vaccine.html  17 https://www.darpa.mil/news/2024/rbc-factory  16 https://www.src.org/program/grc/semisynbio/semisynbio-consortium-roadmap/  15 https://www.scsp.ai/2023/04/scsps-platform-panel-releases-national-action-plan-for-u-s-leadership-in-biotechnology/  14 https://dnastoragealliance.org/  13 https://www.mycoworks.com/  12 https://serdp-estcp.mil/focusareas/3b64545d-6761-4084-a198-ad2103880194  11  https://zbiotics.com/  10 https://www.norfolkhealthyproduce.com/  9 https://light.bio/     8 https://web.archive.org/web/20250116082806/https:/www.whitehouse.gov/wp-content/uploads/2024/11/BUILDIN G-A-VIBRANT-DOMESTIC-BIOMANUFACTURING-ECOSYSTEM.pdf  7 https://www.mckinsey.com/industries/life-sciences/our-insights/the-bio-revolution-innovations-transforming-econo mies-societies-and-our-lives     6 https://www.nationalacademies.org/our-work/safeguarding-the-bioeconomy-finding-strategies-for-understanding-ev aluating-and-protecting-the-bioeconomy-while-sustaining-innovation-and-growth   5 https://doi.org/10.1038/s41586-020-2650-9  

  4 https://www.nature.com/articles/s41467-023-40199-9

AIH- May 2025.Billion Asian womens end poverty networking 2006-1976 is most exciting case of Entrepreneurial Revolution (survey Xmas 1976 Economist by dad Norman Macrae & Romano Prodi). In 2007, dad sampled 2000 copies of Dr Yunus Social Business Book: and I started 15 trips to Bangladesh to 2018- many with apprentice journalists. This is a log of what we found - deepened after dad's death in 2010 by 2 kind remembrance parties hoist by Japan Embassy in Dhaka with those in middle of digital support of what happened next. We witnessed a lot of conflicts - i can try and answer question chris.macrae@yahoo.co.uk or see AI20s updates at http://povertymuseums.blogspot.com. I live in DC region but see myself as a Diaspoira Scot. Much of dad's libraries we transfreered with Dr Yunus to Glasgow University and enditirs og journals of social business, new economics and innovators of Grameen's virtual free nursing school.
Bangladesh offers best intelligence we have seen for sdgs 5 through 1 up to 2008, Search eg 4 1 oldest edu 4.6 newest edu ; .620th century intelligence - ending poverty of half world without electricity -although Keynes 1936 (last chapter General Theiory: Money, Interest, Employment) asked Economists to take hippocratic oath as the profession that ended extreme poverty, most economists have done the opposite. What's not understandable is how educators failed to catalogue the lessons of the handful who bottom-up empowered villages to collaboratively end poverty. There are mainly 2 inteligences to understand- Borlaug on food science -arguable the forst Biointeligence rising ar1950 on; fazle abed on everything that raised life expectancy in tropical village (zero-electricity) asia from low 40s to 60s (about 7 below norm of living with electricity and telecomes). Between 1972 and late 1990s, Abed's lessons catalogued in this mooc had largely built the nation of Bangladesh and been replicated with help of Unicef's James Grant acroo most tropical asian areas. What's exciting is the valley's mr ad mrs steve jobs invted Fazle Abed to share inteligences 2001 at his 65th birthday party. The Jobs and frineds promised to integrate abed's inteligence into neighborhod university stanfrd which in any event wanted Jobs next great leap the iphone. The Valley told abed to start a university so that women graduates from poor and rich nations could blend inteligence as Abed's bottom of the pyramid vilage began their journey of leapfrog modles now that grid infrastructures were ni longer needed for sdiar and mobile. Abed could also help redesign the millennium goals which were being greenwashed into a shared worldwide system coding frame by 2016. There at Abed's 80th birtday party , the easy bit was checking this mooc was uptodate. The hard bit - what did Abed mean by his wish to headhunt a Taiwanese American to head the university's 3rd decade starting 2020?

Wednesday, April 30, 2025

 24-25 was extraordinary YEAR FOR SCIENCE DIPLOMACY OUT OF dc

special thanks to embassies

German in NY Join us for insightful breakout sessions covering crucial topics like Multilateral Research Collaboration from the perspectives of academia and science funding agencies, S&T partnerships with the EU, and Poland International Partnerships. Delve into Bilateral and Multilateral Opportunities in STI Partnerships with our Head of Programs, Jan Lüdert, and esteemed speakers from the Embassy of Poland, Delegation of EU to the United States, NSF, MIT International Science and Technology Initiatives, U.S. Global Change Research Program, and U.S. Department of State.

April 14, 2025 2:00 PM-4:30 PM ET: Track Agenda (More info here)

2:00-2:10 pm Introductory Remarks

2:15-2:45 pm Multilateral Research Collaboration: Academia & Science Funding Agencies Perspectives | Format: panel Speakers: Roxanne Nikolaus, Mika Takagi and Andreas Göthenberg  Moderator: Sudeep Kanungo

2:50-3:20 pm S&T Partnerships with the EU |Format: talk Speaker: Florent Bernard

4:00-4:30 pm Poland International Partnerships |Format: TBA Speaker: Katarzyna Granat

4:00-4:30 pm Bilateral and Multilateral Opportunities in STI Partnerships | Format: fireside chat Speaker: Jan Lüdert, Juliet Gerrard and Eugenio Vargas Garcia Moderator: Connie Bolte


Yesterday I had the honor of putting children front and center during the Science Diplomacy Summit in DC at Johns Hopkins University Bloomberg Center, sharing how everyone.AI and the Paris Peace Forum are pushing for Beneficial AI that truly serves children.

I am grateful for the Embassy of France in the United States and for Mireille Guyader and Joaquim Nassar at the French Embassy for giving this issue the spotlight it deserves. Children make up a quarter of the world’s population—ignoring them in AI talks isn’t an option. Thank you Philippe Ribière for guiding our conversation on how science‑driven design can unlock AI’s promise while mitigating age-specific risks for young users.

Thank you, Joshua Broadwater for curating an AI track packed with brilliant minds in the field of AI and diplomacy, it was truly a privilege to share the stage with Yann LeCun, Michal Pechoucek, Luke Stevens, Eugenio V Garcia.

I left with so many insights and a handful of new partnerships in the works. If we swapped ideas on ethics guidelines, joint grants, or coalition projects—expect a follow‑up. If we missed each other, my DMs are always open!

Finally, hats off to Ona Ambrozaite, Ph.D. for running the summit with contagious energy and genuine warmth—her passion filled the room and made everyone feel instantly welcome. Nothing beats the spark that comes from being in the same room with people who share the same passion for driving positive impact.

ARTIFICIAL INTELLIGENCE, DISEMBODIED WISDOM: INTERVIEW WITH DR MATHILDE CERIOLI

“[...] humans, people and knowledge are not only objectively significant: they are by far the most significant phenomena in nature – the only ones whose behaviour cannot be understood without understanding everything of fundamental importance.”

― David Deutsch, The Beginning of Infinity: Explanations That Transform the World

 

 


 

As AI becomes increasingly more of an influence in many realms of life at higher speeds than expected - whether we are thinking about loss of jobs and the ripple effects of that into the economy, or tech addiction and the belief-behavior manipulation that AI is capable of, there are new realms of exploration that will also become important to us. 

This is especially the case if we wish to create conditions for ourselves that will sustain us into the future in terms of jobs/work, lifestyle, mental health and Human Thriving.


Listen on Spotify

Listen on Apple Podcast

 

 


The beauty of Artificial Intelligence is that it pushes us to also more deeply understand the nature of Intelligence itself. 

What is intelligence and how are humans set apart from other species and machines?*  As physicist David Deutsch says, we are universal constructors - our intelligence is generalized and generalizable - making us capable of adapting to any corner of any ecosystem.

*(I’ll be covering the concept of intelligence in an upcoming episode)

 

Intelligence is a complex notion.  Marvin Minsky, an AI pioneer, in a 1998 interview with Edge, talked about intelligence as a "suitcase word":

“all of us use these [terms] to encapsulate our jumbled ideas about our minds. We use those words as suitcases in which to contain all sorts of mysteries that we can’t yet explain.”

 

Like a suitcase that's packed full of many different things, some are related, some aren't. Melanie Mitchell of the Santa Fe institute also reflects this In a SFI podcast series on intelligence:

there's no single thing that intelligence is. It's a whole bunch of different capabilities and ways of being that perhaps are not just one single thing that you could either have more of or less of or get to the level of something. It's much more of a complex notion. There's a lot of different hallmarks that people think of when they think of intelligence” 

 


 The more we talk about intelligence the more we might see a few key themes emerge...

  1. That humans are still pretty special in terms of what we are able to do with our minds and bodies;
  2. That the word intelligence is a ‘suitcase word’ and that it is such a complex notion that even trying to define it helps us explore our own and others’ paradigms and capacities for complex perspectives;
  3. That the body and embodied intelligence are massively important and often ignored a missing from many explorations about intelligence;
  4. The more we talk about complexity and explore the Nature of Intelligence, the better chance me have at designing Systems and Environments that actually facilitate on highest capacities for learning, resilience and adaptation

 


Our human intelligence, unlike AI, is embodied… it is enfleshed and interacts with sensory-motor, visceral-kinesthetic, skeleto-muscular systems. 

Conversely, AI can only use the inputs we - as humans- give it for how it learns (at least currently).

Even the highest definition 3D rendering doesn't have smell, taste, texture or pressure.. 

The inputs AI works with is not the actual visceral, in-the-body-experience.  There are no internal bodily fluctuations of heart rhythms, ears ringing, cheeks flushing, skin electrifying experiences that it lives.
It only gets our translations of those as words, code and images. 

 

This means that its data is 'one layer out’ from our actual experience. 

It is in the symbolic realm - where the actual sensations of life have been translated into the best attempts we have to convey them. But symbols aren't the experience. They can only represent the experience. What is fed into the pool of data for AI  doesn’t include smell, texture, heat, pressure, etc.   A picture or description of a windy or rainy day doesn’t contain the movement, feel of wind, rain, the variety of smells that get stirred up.

AI relies on what we feed into it. And what we feed into it is not our actual visceral experiences, but how we interpret them, what we notice and how we take all that and try to put all that into words and images. 

 


Humans perceive what HUMANS perceive through the vibrational and sensory mechanisms we have in our tissues and organs.  

We then do our best to translate those experiences.  

Not only will those translations be imperfect, they will only be based on what we NOTICE. 

There are FREQUENCIES that coexist with us at every moment we are completely unaware of and therefore are not capable of being inputted into a digital system.  AI can only work with the limitations we ourselves have on representing and conveying our own experiences. 

There are also PERSPECTIVES that we are also completely unaware of and that are therefore also not capable of being inputted into a digital system.

 

This means that what AI uses to form its own intelligence is disconnected from our deepest, most visceral and sensory, mammalian and flesh-based existence.

What this means for us is that we must truly get to KNOW OURSELVES… who we truly are as embodied, intelligent beings... how we use our bodies, minds and sensations to adapt constantly - in ways that help us align with how we truly want to FEEL and experience life inside our bodies.. 

 


AI is a topic that matters to ALL OF US whether we realize it or not.

Because it IS real.  And there is an intelligence to it that can help us in powerful ways, and can have detrimental effects beyond what we can currently even imagine. As Mathilde states in an interview with KidsAI:

“for the first time, machines can interact with us in ways that sound human. This directly taps into human vulnerabilities, as we are prone to this bias and often quickly forget that we are not interacting with a human being.” - Dr. Mathilde Cerioli

 

The Problem with Counterfeit People

This anthropomorphism is one of the key areas of concern for Dr. Mathilde Cerioli, as well as other other experts.  We might trust AI with things that it shouldn’t have agency over, and we are seeing negative impacts from this.  

As the late philosopher Daniel Dennett states in his article "The Problem with Counterfeit People"

"Today, for the first time in history, thanks to artificial intelligence, it is possible for anybody to make counterfeit people who can pass for real in many of the new digital environments we have created."

 


In this episode, Dr. Mathilde Cerioli, Chief Scientist at everyone.ai and I explore ideas of trust, emotional manipulation and other impacts of AI on human development. 

Mathilde holds a Ph.D. in Cognitive Neuroscience and a Master's Degree in Psychology, with a strong focus on child development. Her research focuses on the intersection of AI and child cognitive and socio-emotional development. She is the Chief Scientific Officer at everyone.AI, a nonprofit focused on educating about the opportunities and risks of AI for children. Within everyone.ai and in partnership with the Paris Peace Forum, she contributed to the launch of the Beneficial AI for Children Coalition, a multistakeholder initiative that aims to orient the development, deployment and adoption of beneficial AI for children and adolescents, working with 11 governments, tech companies, and large organizations and NGOs, such as UNICEF, UNESCO and Common Sense Media.

In our conversation, we touch on what artificial intelligence is, and what kind of impact we are seeing it have particularly in the realm of how it can negatively impact human learning, behavior and the negative impacts it can have on mental health especially for young people.  

As she states: 

one of the big concerns with some of the AI programs we are seeing now is that it can create an extremely "highly engaged ‘parasocial’ relationship with someone", but... they are now interacting "with an entity that lacks reciprocity at critical moments...” 

 

This type of dynamic is particularly dangerous for yougn people, whose brains are still developing. 

Another key part of  conversation is that Mathilde highlights one of the biggest misunderstandings she sees with many learning apps and gamifications: they seem to assume that they need to make learning more fun by adding prizes, points, rewards, etc.  When in fact, as she asserts, learning and mastery are inherently rewarding .. 

 


Change can often be facilitated by ‘better questions’...

A 'better' (more nuanced, systems-oriented) question to be asking, potentially, is whether these apps and games actually facilitate learning.  Or, are they designed with a similar goal as many other apps: to keep people engaged on the app.  

Not only is it important for us to think about the GOAL of what people are designing Al to do, we can also ask:

  • Who are the humans behind the algorithms and programs being designed? 
  • What are their experiences and backgrounds? 
  • What kind of exposure have they had to the vast spectrum of human cultures, and developmental insights? 

 


AI isn’t going anywhere.  It will only get more sophisticated and prevalent in our world. This doesn’t have to be a bad thing.  

We can use this incredible technology for enormous good.  What it pushes us to do now, is to understand - as deeply and with as much curiosity as we can - what we truly need to thrive as individuals and as a collective.  It presents an opportunity for us to dive into what makes humans special, intelligent, curious and connected 

 

 


“In general, we’re least aware of what our minds do best.”

― Marvin Minsky, The Society of Mind




 

References (please also see hyperlinks in the above article for resources):

Deutsch, D. (2011). The beginning of infinity: Explanations that transform the world. New York: Viking.

Minsky, M. (1986). The society of mind. Simon & Schuster, New York, NY. 

Poole, D. L., & Mackworth, A. K. (2023). Artificial Intelligence: Foundations of Computational Agents (3rd ed.). Cambridge: Cambridge University Press. 

 

 

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