INTELLIGENCE ENGINEERING'S ALPHABET : World Class Biobrains: Drew Endy, Matt Scullin, Daniel Swiger++- BI BioIntelligence, the most collaborative human challenge Mother Earth has ever staged?
NB any errors below are mine alone chris.macrae@yahoo.co.uk but mathematically we are in a time when order of magnitude ignorance can sink any nation however big. Pretrain to question everything as earth's data is reality's judge
Its time to stop blaming 2/3 of humans who are Asian for their consciously open minds and love of education. Do Atlantic people's old populations still trust and celebrate capability of generating healthy innovative brains? What's clear to anyove visting Washington DC or Brussels is a dismal mismatch exists between the gamechanging future opportunities listed below and how freedom of next generation learning has got muddled by how old male-dominated generations waste money on adevrtising and bossing. Consider the clarity of Stanford's Drew Endy's Strange Competition 1 2:
Up to “60% of the physical inputs to the global economy”7 could be made via biotechnology by mid-century, generating ~$30 trillion annually in mostly-new economic activity. 8 Emerging product categories include consumer biologics (e.g., bioluminescent petunias,9 purple tomatoes,10 and hangover probiotics11 ), military hard power (e.g., brewing energetics12 ), mycological manufacturing (e.g., mushroom ‘leather’ 13 ), and biotechnology for technology (e.g., DNA for archival data storage14 ). Accessing future product categories will depend on unlocking biology as a general purpose technology15 (e.g., growing computers16 ), deploying pervasive and embedded biotechnologies within, on, and around us (e.g. smart blood,17 skin vaccines,18 and surveillance mucus19 ), and life-beyond lineage (e.g., biosecurity at birth,20 species de-extinction21 ).
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notes on drew endy testimony on bio tech 2025 strange competition

Natural living systems operate and manufacture materials with atomic precision on a planetary scale, powered by ~130 terawatts of energy self-harvested via photosynthesis

Biotechnology enables people to change biology. Domestication and breeding of plants and animals for food, service, and companionship began millennia ago. Gene editing, from recombinant DNA to CRISPR, is used to make medicines and foods, and is itself half-a-century old. Synthetic biology is working to routinize composition of bioengineered systems of ever-greater complexity

 https://colossal.com/  20 https://dspace.mit.edu/handle/1721.1/34914  19 https://2020.igem.org/Team:Stanford  18 https://med.stanford.edu/news/all-news/2024/12/skin-bacteria-vaccine.html  17 https://www.darpa.mil/news/2024/rbc-factory  16 https://www.src.org/program/grc/semisynbio/semisynbio-consortium-roadmap/  15 https://www.scsp.ai/2023/04/scsps-platform-panel-releases-national-action-plan-for-u-s-leadership-in-biotechnology/  14 https://dnastoragealliance.org/  13 https://www.mycoworks.com/  12 https://serdp-estcp.mil/focusareas/3b64545d-6761-4084-a198-ad2103880194  11  https://zbiotics.com/  10 https://www.norfolkhealthyproduce.com/  9 https://light.bio/     8 https://web.archive.org/web/20250116082806/https:/www.whitehouse.gov/wp-content/uploads/2024/11/BUILDIN G-A-VIBRANT-DOMESTIC-BIOMANUFACTURING-ECOSYSTEM.pdf  7 https://www.mckinsey.com/industries/life-sciences/our-insights/the-bio-revolution-innovations-transforming-econo mies-societies-and-our-lives     6 https://www.nationalacademies.org/our-work/safeguarding-the-bioeconomy-finding-strategies-for-understanding-ev aluating-and-protecting-the-bioeconomy-while-sustaining-innovation-and-growth   5 https://doi.org/10.1038/s41586-020-2650-9  

  4 https://www.nature.com/articles/s41467-023-40199-9

AIH- May 2025.Billion Asian womens end poverty networking 2006-1976 is most exciting case of Entrepreneurial Revolution (survey Xmas 1976 Economist by dad Norman Macrae & Romano Prodi). In 2007, dad sampled 2000 copies of Dr Yunus Social Business Book: and I started 15 trips to Bangladesh to 2018- many with apprentice journalists. This is a log of what we found - deepened after dad's death in 2010 by 2 kind remembrance parties hoist by Japan Embassy in Dhaka with those in middle of digital support of what happened next. We witnessed a lot of conflicts - i can try and answer question chris.macrae@yahoo.co.uk or see AI20s updates at http://povertymuseums.blogspot.com. I live in DC region but see myself as a Diaspoira Scot. Much of dad's libraries we transfreered with Dr Yunus to Glasgow University and enditirs og journals of social business, new economics and innovators of Grameen's virtual free nursing school.
Bangladesh offers best intelligence we have seen for sdgs 5 through 1 up to 2008, Search eg 4 1 oldest edu 4.6 newest edu ; .620th century intelligence - ending poverty of half world without electricity -although Keynes 1936 (last chapter General Theiory: Money, Interest, Employment) asked Economists to take hippocratic oath as the profession that ended extreme poverty, most economists have done the opposite. What's not understandable is how educators failed to catalogue the lessons of the handful who bottom-up empowered villages to collaboratively end poverty. There are mainly 2 inteligences to understand- Borlaug on food science -arguable the forst Biointeligence rising ar1950 on; fazle abed on everything that raised life expectancy in tropical village (zero-electricity) asia from low 40s to 60s (about 7 below norm of living with electricity and telecomes). Between 1972 and late 1990s, Abed's lessons catalogued in this mooc had largely built the nation of Bangladesh and been replicated with help of Unicef's James Grant acroo most tropical asian areas. What's exciting is the valley's mr ad mrs steve jobs invted Fazle Abed to share inteligences 2001 at his 65th birthday party. The Jobs and frineds promised to integrate abed's inteligence into neighborhod university stanfrd which in any event wanted Jobs next great leap the iphone. The Valley told abed to start a university so that women graduates from poor and rich nations could blend inteligence as Abed's bottom of the pyramid vilage began their journey of leapfrog modles now that grid infrastructures were ni longer needed for sdiar and mobile. Abed could also help redesign the millennium goals which were being greenwashed into a shared worldwide system coding frame by 2016. There at Abed's 80th birtday party , the easy bit was checking this mooc was uptodate. The hard bit - what did Abed mean by his wish to headhunt a Taiwanese American to head the university's 3rd decade starting 2020?

Saturday, July 31, 2021

tb 3.4 tuberculosis dots TB

  http://www.brac.net/program/health-nutrition-and-population/tuberculosis-and-malaria-control/

Tuberculosis Control

Tuberculosis (TB) has been a major public health concern for Bangladesh for decades. According to the World Health Organization (WHO), Bangladesh ranks seventh among the 22 highest TB-burdened countries. BRAC initiated the tuberculosis control programme in 1984 in one district as a pilot. In 1994, BRAC became the first NGO in the country to sign a memorandum of understanding with the government to expand directly observed treatment short course (DOTS) services across the country. BRAC also became a principle recipient (PR) of the Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), along with the government. The aim of the programmeis to reduce the morbidity, mortality and transmission of TB until it is no longer a public health problem.

BRAC's shasthya shebikas(frontline community health worker) play a pivotal role inconnecting individuals with TB control services during household visits and health forums. They disseminate TB-specific messages to the community, identify presumptive TB patients and refer them, for sputum examination, to the governmen tsub-district health complex or peripheral laboratories of BRAC. The frontline health workers also ensure regular intake of medicine for identified TB patients through DOTS. They refer complicated TB patients to health facilities for further treatment and for proper management of side effects and other complications during TB treatment.

BRAC's approach towards the diagnosis and treatment of TB focuses on community level education and engagement. The programme conducts orientation with different stakeholders of the community to engage them in efforts to identify TB patients, ensure treatment adherence, and reduce stigma surrounding TB. The stakeholders include cured TB patients, local religious leaders, school going children, girls' guides and scouts, other NGO workers, formal and non-formal care providers like graduate private practitioners, village doctors and pharmacists.

Currently, BRAC covers 297 sub-districts from 42 districts, 7 city corporations with a population of 92.9 million people including 31 academic institutes, 41 prisons, 405 peripheral laboratories and 26 external quality assessment centres. BRAC is leading a group of 42 local NGOs who are the sub -recipients (SRs) of the GFATM under the same umbrella of NTP. BRAC supervises, monitors, guides and provides technical assistance to the SRs,to ensure that the quality of the service delivered is uncompromised.

 

Malaria Control

Malaria is a major public health problem in some parts of Bangladesh, particularly in 13 districts in the north-east & south-east areas which border India and Myanmar. Among them are the Chittagong hill tracts (CHT) districts which highly endemic and Cox’s Bazar which is moderately endemic. The other districts are categorised as low endemic areas as fewer numbers of cases have been reported there. Sporadic incidences occur in other parts of the country.

The National Malaria Control Programme (NMCP) established an effective partnership with a consortium of 21 NGOs led by BRAC. This partnership has leveraged the programme and increased the access to malaria treatment, prevention and awareness raising activities within communities, including the hard-to-reach areas.

In partnership with the National Malaria Control Programme (NMCP), BRAC successfully secured a grant from the GFATM to strengthen and expand national malaria control activities to all endemic districts working directly and through other NGOs. BRAC is directly implementing malaria control activities in all sub districts of CHT, two sub districts of Moulvibazar, and through 20 partner NGOs in other districts which are monitored and supervised by BRAC. To reduce the overall burden of malaria (morbidity and mortality) by 60 percent from baseline year 2008 in 10.9 million populations in 13 high endemic districts of Bangladesh by 2015.

Goal

To reduce the overall burden of malaria (morbidity and mortality) in the 13 high endemic districts of Bangladesh by 60 percent, by the year 2015.

Objectives

  • To expand the use of Long Lasting Insecticidal bed Nets (LLIN)( two nets per household), to achieve 100 percent coverage in the three malaria endemic districts and to maintain 80 percent coverage with Insecticide Treated bed Nets (ITN)/LLIN in the remaining districts.
  • To expand and improve the quality of diagnosis and treatment of malaria cases to 90 percent.
  • To further strengthen programme management and partnership coordination surrounding malaria control.

BRAC’s community based model has been applied in malaria programmes to promote health education, empowerment and home based services. BRAC’s shasthyashebikas and shasthyakormis diagnose malaria patients using a Rapid Diagnostic Test (RDT) kit, therefore providing treatment at a household level They also refer patients to the nearest government health facilities in case of pregnant women, children under five kilograms of weight and severe malaria cases. In addition, 121 laboratories and sub-centres have been established in remote areas to strengthen early diagnosis and prompt treatment (EDPT). LLINs are distributed in the community free of cost as one of the most important methods of preventing the transmission of malaria.

Various sensitisation and advocacy meetings are conducted among the different stakeholders of the community to make them aware of malaria symptoms and to engage them in the effort to identify patients, increase utilisation of LLIN and to create early care seeking behaviour. The stakeholders include local figures, religious leaders, headmen, karbaris, teachers, village doctors, pharmacists, private practitioners and hotel owners/ managers.

Since May 2007 to June 2014, a total of 3,067,663 cases of fever were examined nationally by RDT and/or microscopy, of which BRAC and its partner NGOs performed 1,822,086. Out of 318,649 confirmed malaria cases, 228,233 (72%) were treated at the community level in the same period. In addition, death due to malaria was reduced by 90 percent (15) in 2013 in comparison with the baseline year 2008 (154). Since the beginning of the programme, a total of 3,735,905 LLINs have been distributed among the beneficiaries in the malaria endemic areas.

Download: National Malaria Treatment Regimen 2016

Malaria Funding Request (2021-2023) to The Global Fund
We are pleased to upload Malaria National Strategic Plan (NSP) and The Global Fund Funding Request 2021-2023 for your kind feedback and comments. It will be highly appreciated if you kindly share your feedback by 08 March 2020.

· Dr Afsana Alamgir Khan, DPM, National Malaria Elimination Programme: afsanak.nmepdpm@gmail.com
· Dr Shayla Islam, Programme Head, Communicable Diseases (Malaria) Programme, BRAC: shayla.i@brac.net
· Manaj Kumar Biswas, BCCM Coordinator: bccmcoordinator@gmail.com

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